The thought here is that enzymes push around their substrates. They grab hold and put them in seemingly uncomfortable positions making them more vulnerable for reactions. I imagine a poor substrate having its 'arm' yanked up behind it as the bullying enzyme forces it to scream, "Bob's my uncle!" I know, it's unsettling, but our very own metabolic pathways are based on barbaric bullying tactics. Shame on you and shame on me too.
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The thought here is that enzymes push around their substrates. They grab hold and put them in seemingly uncomfortable positions making them more vulnerable for reactions. I imagine a poor substrate having its 'arm' yanked up behind it as the bullying enzyme forces it to scream, "Bob's my uncle!" I know, it's unsettling, but our very own metabolic pathways are based on barbaric bullying tactics. Shame on you and shame on me too.
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